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long-term neurodegenerative effects of injection

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Geremia:
Long-term neurodegenerative effects were predicted in a 2012 paper:

Oliver D. King, Aaron D. Gitler, and James Shorter, “The Tip of the Iceberg: RNA-Binding Proteins with Prion-like Domains in Neurodegenerative Disease,” Brain Research 1462 (June 2012): 61–80.


--- Quote from: Abstract ---Prions are self-templating protein conformers that are naturally transmitted between individuals and promote phenotypic change. In yeast, prion-encoded phenotypes can be beneficial, neutral or deleterious depending upon genetic background and environmental conditions. A distinctive and portable ‘prion domain’ enriched in asparagine, glutamine, tyrosine and glycine residues unifies the majority of yeast prion proteins. Deletion of this domain precludes prionogenesis and appending this domain to reporter proteins can confer prionogenicity. An algorithm designed to detect prion domains has successfully identified 19 domains that can confer prion behavior. Scouring the human genome with this algorithm enriches a select group of RNA-binding proteins harboring a canonical RNA recognition motif (RRM) and a putative prion domain. Indeed, of 210 human RRM-bearing proteins, 29 have a putative prion domain, and 12 of these are in the top 60 prion candidates in the entire genome. Startlingly, these RNA-binding prion candidates are inexorably emerging, one by one, in the pathology and genetics of devastating neurodegenerative disorders, including: amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U), Alzheimer's disease and Huntington's disease. For example, FUS and TDP-43, which rank 1st and 10th among RRM-bearing prion candidates, form cytoplasmic inclusions in the degenerating motor neurons of ALS patients and mutations in TDP-43 and FUS cause familial ALS. Recently, perturbed RNA-binding proteostasis of TAF15, which is the 2nd ranked RRM-bearing prion candidate, has been connected with ALS and FTLD-U. We strongly suspect that we have now merely reached the tip of the iceberg. We predict that additional RNA-binding prion candidates identified by our algorithm will soon surface as genetic modifiers or causes of diverse neurodegenerative conditions. Indeed, simple prion-like transfer mechanisms involving the prion domains of RNA-binding proteins could underlie the classical non-cell-autonomous emanation of neurodegenerative pathology from originating epicenters to neighboring portions of the nervous system.
--- End quote ---
cf. this related 2011 paper

Geremia:
my friend's description of the 2012 paper:

--- Quote ---Here attached is a fascinating paper dating from 2012 (in its unedited form accepted for publication). It is entitled: The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

It is especially relevant in light of the growingly known fact that RNA injections (like the non-vaccinal Covid injection) are causatively linked to a multitude of late-emerging chronic diseases of a neurological nature (way worse than catching a flu).
 
You will keep in mind that the Pfizer-made Covid “vaccine” (which is now the standard Covid injection around the world) was in fact evaluated for its ability to convert the TDP-43 protein (a DNA-binding protein) and/or the FUS protein (a RNA-binding protein) into their pathogenic state capable of triggering prion-based diseases. Pfizer specifically analyzed its non-vaccinal synthetic creation (now known as the “Pfizer-BioNTech COVID-19 Vaccine”) for the presence of sequences capable of activating TDP-43 and FUS.
 
Its own analysis has identified two potential key risk factors capable of inducing prion disease in man. Meaning, it is public knowledge that the Pfizer’s RNA-based COVID-19 injection contains many of these RNA sequences which have been shown to have a high affinity for TDP-43 or FUS proteins; and thus have the potential to trigger the development of common chronic neurodegenerative diseases (as has long been known of this type of RNA sequence-based technology, see also this equally relevant 2011 paper).
 
Going back to the attached 2012 paper, the combination of TDP-43 and FUS into their prion-like configuration Pfizer bioengineering has focused its recent analysis on is clearly nothing that has not already been known and well-understood. The research has been pursued and has yielded significant results, enough to form the basis for a strong recommendation against the Covid injection (not mentioning here all the other reasons for one’s educated resistance against and rejection of the vaccinal propaganda for the last several months of ongoing Covidism).
 
As useless as all of this informational effort is bound to prove as this stage of the game, feel free to still pass it on.
 
God bless and protect everyone.
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Insanis:
mRNA breaks down quickly. The whole complication of mRNA based vaccinations was the delivery system: to ensure it wouldn't be destroyed before causing an immune response.

The question scientists are having is more about how long the effect lasts and ensuring that the mRNA doesn't break down before it is used.

Our bodies deal with faulty DNA and RNA and foreign genetic materials all the time.

Prions are a very serious and rare disorder. Anyway, even if the vaccinations cause prion diseases, that means that about half the population in the USA is doomed.

But, beware of just linking studies and speculation based on keywords.

It is like saying WiFi transmissions can cook you just because they usually use the same frequency as microwave ovens (2.4 GHz). One needs to have a relevant background to interpret studies properly.

Otherwise, it is just keyword fear mongering.

I prefer to think: what is more likely? That greedy, selfish, and power hungry people will kill 70% of the population when their goals require people to be around to give the money? Or that they did their best to make a product that will work and increase their shareholder value and profits?

The question about these vaccines they are asking is if they last more than 6 months, not whether they last forever.



Geremia:

--- Quote from: Insanis on May 25, 2021, 03:00:06 PM ---That greedy, selfish, and power hungry people will kill 70% of the population when their goals require people to be around to give the money? Or that they did their best to make a product that will work and increase their shareholder value and profits?
--- End quote ---
Those are two different questions?

Insanis:

--- Quote from: Geremia on May 25, 2021, 06:52:41 PM ---
--- Quote from: Insanis on May 25, 2021, 03:00:06 PM ---That greedy, selfish, and power hungry people will kill 70% of the population when their goals require people to be around to give the money? Or that they did their best to make a product that will work and increase their shareholder value and profits?
--- End quote ---
Those are two different questions?

--- End quote ---

Yes. They want people to buy from them and want economic growth. Killing people goes against that.

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